WHO WE ARE

PPD ACT Researchers

PPD ACT is a research study developed by Postpartum Depression: Action Towards Causes and Treatment (PACT) Consortium, an international group of academic clinicians and scientists committed to understanding the interaction of genes and environment to predict which women are at risk of postpartum depression (PPD).

We are working together to engage women who currently have or had postpartum depression or postpartum psychosis in a genetics research study using our free iOS and free android mobile app, PPD ACT, which is currently available in Australia, Canada, and the US, and coming soon to the UK and to Denmark.

Researchers in the Departments of Psychiatry and Genetics at the University of North Carolina at Chapel Hill who are PACT Consortium members are leading PPD ACT and overseeing the US arm of the study. Researchers from Queensland Brain Institute at the University of Queensland, and University of Toronto oversee the Australian and Canadian arms of the study that are now active. Researchers from the National Centre for Mental Health at Cardiff University and Aarhus University will launch PPD ACT in the UK and Denmark later in 2017.

Meet the Teams

PACT US Team




LEFT TO RIGHT: Patrick Sullivan, Jerry Guintivano, Samantha Meltzer-Brody, Carol Lewis, Holly Krohn at University of North Carolina at Chapel Hill
PACT Australia Team
The PACT Australia team is composed of several different institutions, including Naomi Wray and team at Queensland.

Bernhard Baune

Anne Buist

Enda Byne

Ian Hickie

Julio Licinio

Nick Martin

Jeannette Milgrom

Naomi Wray

The Australian arm of the PPD ACT study is designed to collect more detailed information about health and lifestyle as part of our "Genetics of Risk and Response to Treatment of Depression" study. You can find more information on the study website.

PACT Canada Team
The PACT Canada team is composed of the following contributors:

Benicio Frey

Cindy-Lee Dennis

Jim Kennedy

Ryan Van Lieshout

Simone Vigod

Sophie Grigoriadis

Tim Oberlander

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PACT UK Team
The PACT UK team is associated with National Centre for Mental Health and Cardiff University.
PACT Denmark Team


The PACT Denmark team is associated with National Center for Register-Based Research, Aarhus University.

Sponsors

UNC School of Medicine
The UNC School of Medicine Departments of Psychiatry and Genetics sponsored the creation of the app. Within the UNC Department of Psychiatry, The team from UNC Center for Women's Mood Disorders provided the infrastructure to create the app. The UNC Health Care and UNC School of Medicine Center for Innovation provided critical project management.
National Institute of Mental Health
The National Institute of Mental Health (NIMH) is the lead federal agency for research on mental disorder focused on transforming the understanding and treatment of mental illnesses through basic and clinical research, paving the way for prevention, recovery, and cure. NIMH is partnering with PPD ACT to provide the spit kits used for DNA collection.
Postpartum Support International
Postpartum Support International was founded in 1987 by Jane Honikman in Santa Barbara, California. The purpose of the organization is to increase awareness among public and professional communities about the emotional changes that women experience during pregnancy and postpartum. Approximately 15% of all women will experience postpartum depression following the birth of a child. Up to 10% will experience depression or anxiety during pregnancy. When the mental health of the mother is compromised, it affects the entire family.
SAGE Therapeutics
SAGE Therapeutics is a neuroscience-focused company discovering medicines to treat life-threatening, rare CNS disorders. Launched in 2010, SAGE is a publicly traded company led by an experienced team of leaders, CNS experts and investors. Our lead program, SAGE-547, is in clinical development for super-refractory status epilepticus (SRSE) and is the first of many in an exciting portfolio of potential seizure medicines.
Foundation of Hope
The Foundation of Hope promotes scientific research aimed at discovering the causes and potential cures for mental illness in order to develop a more effective means of treatment. The Foundation is committed to raising community awareness and supporting effective treatment programs. The Foundation provides financial support for ongoing and new research and treatment, as well as the development of researchers at the University of North Carolina at Chapel Hill, its affiliated psychiatric institutions, and local mental health agencies.



Thank you to our sponsors for all you've contributed!

PACT Members

These are PACT members who have contributed data or scholarship to current PACT projects.

Margaret Altemus

Weill Cornell Medical College, Department of Psychiatry, US
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Robert Ammerman

University of Cincinatti, US
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Gisele Apter

Erasme Hospital, Paris Diderot University, France
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Geena Athappilly

Brigham and Women's Hospital, Harvard Medical School, US
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Jehannine C. Austin

Departments of Psychiatry and Medical Genetics, University of British Columbia, Vancouver, Canada
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Bernhard T. Baune

Discipline of Psychiatry, University of Adelaide, Australia
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Veerle Bergink

Erasmus MC, Department of Psychiatry/Psychology, Rotterdam, The Netherlands
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Justin Bilzta

University of Melbourne, Women's Mental Health, Australia
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Rebecca Brock

The University of Iowa, Department of Psychology, US
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Anne Buist

University of Melbourne, Women's Mental Health, Australia
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Enda Byrne

Queensland Brain Institute, University of Queensland, Australia
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Kristina Deligiannidis

University of Massachusetts Medical School, Department of Psychiatry, US
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Cindy Lee-Dennis

University of Toronto, Centre for Addiction and Mental Health, Canada
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Emmanuel Devouche

Erasme Hospital, Paris Descartes University, France
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Arianna Di Florio

The University of North Carolina at Chapel Hill, US and Cardiff University, UK
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C. Neill Epperson

University of Pennsylvania, Department of Psychiatry, US
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Benicio Frey

St. Josephs Healthcare Hamilton, McMaster University, Canada
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Sophie Grigoriadis

University of Toronto, Department of Psychiatry, Sunnybrook Health Sciences Centre, Canada
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Constance Guille

Medical University of South Carolina, Department of Psychiatry, US
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Jerry Guintivano

The University of North Carolina at Chapel Hill, Department of Psychiatry, US
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Hadine Joffe

Brigham and Women's Hospital, Harvard Medical School, US
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Ian Jones

Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, UK
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James L. Kennedy

Centre for Addiction and Mental Health, University of Toronto, Canada
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Deborah Kim

University of Pennsylvania, Department of Psychiatry, US
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Paul Lichtenstein

Karolinska Institute, Department of Medical Epidemiology and Biostatistics, Sweden
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Patrik Magnusson

Karolinska Institute, Department of Medical Epidemiology and Biostatistics, Sweden
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Pedro Martinez

National Institute of Mental Health, NIH, US
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Samantha Meltzer-Brody

The University of North Carolina at Chapel Hill, Department of Psychiatry, US
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Jeannette Milgrom

University of Melbourne, Australia
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Trine Munk-Olsen

Aarhus University, Department of Economics and Business (NCRR), Denmark
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Maria Muzik

Department of Psychiatry, University of Michigan, US
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Jeff Newport

University of Miami, Department of Psychiatry, US
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Tim Oberlander

BC Children’s and Women’s Health Centre of British Columbia, Canada
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Michael O'Hara

The University of Iowa, Department of Psychology, US
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Jennifer Payne

The Johns Hopkins University, Department of Psychiatry, US
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Brenda Penninx

VU University Medical Center, Department of Psychiatry, The Netherlands
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Karen Putnam

The University of North Carolina at Chapel Hill, Department of Psychiatry, US
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Natalie Rasgon

Department of Psychiatry, Stanford University, US
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Thalia Robakis, MD

Department of Psychiatry, Stanford University, US
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Emma Robertson-Blackmorek

University of Florida at Jacksonville, Department of Psychiatry, US
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Sabine Roza

Erasmus MC, Department of Psychiatry/Psychology, Rotterdam, The Netherlands
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David Rubinow

The University of North Carolina at Chapel Hill, Department of Psychiatry, US
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Peter Schmidt

National Institute of Mental Health, NIH, US
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Katherine Sharkey

Alpert Medical School of Brown University/Rhode Island Hospital, Department of Psychiatry, US
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Meir Steiner

Professor Emeritus, Department of Psychiatry, McMaster University, Canada
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Zach Stowe

University of Arkansas for Medical Sciences, Department of Psychiatry, US
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Scott Stuart

The University of Iowa, Department of Psychology, US
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Patrick Sullivan

The University of North Carolina at Chapel Hill, Department of Psychiatry, US
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Valerie Taylor

Women's College Research Institute, Women's College Hospital, Department of Medicine, Canada
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Henning Tiemeier

Erasmus MC, Department of Psychiatry/Psychology, Rotterdam, The Netherlands
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Ryan Van Lieshout

St. Josephs Healthcare Hamilton,McMaster University, Canada
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Simone Vigod

Women's College Hospital, Department of Psychiatry, University of Toronto, Canada
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Alexander Vikorin

Karolinska Institute, Department of Medical Epidemiology and Biostatistics, Sweden
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Katherine Wisner

Northwestern University Feinberg School of Medicine, Asher Center for the Study and Treatment of Depressive Disorders, US
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Naomi Wray

University of Queensland, Australia
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Developers